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Targeted lipidomics of prostaglandins and leukotrienes in a rat model of LPS-induced systemic inflammation
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| dc.contributor.author | Fonseca, Monique |
| dc.contributor.author | Moretti, Eduardo |
| dc.contributor.author | Marques, Lucas |
| dc.contributor.author | Machado, Bianca |
| dc.contributor.author | Brito, Camila |
| dc.contributor.author | Guedes, Jady |
| dc.contributor.author | Komegae, Evilin |
| dc.contributor.author | Vieira, Thayna |
| dc.contributor.author | Festuccia, William |
| dc.contributor.author | Lopes, Norberto |
| dc.contributor.author | Steiner, Alexandre |
| dc.date.accessioned | 2021-03-25T20:44:19Z |
| dc.date.available | 2021-03-25T20:44:19Z |
| dc.date.issued | 2021-03-25T17:44:19Z |
| dc.identifier.citation | Fonseca, Moretti et al. A leukotriene-dependent spleen-liver axis drives TNF production in systemic inflammation. Science Signaling, in revision. |
| dc.identifier.uri | http://repositorio.uspdigital.usp.br/handle/item/262 |
| dc.description | Known prostaglandins (PG), leukotrienes (LT) and their metabolites were analyzed by LC-MS/MS in plasma and organ samples harvested 80 min after an injection of LPS (1 mg/kg i.v.). In addition to the control LPS-injected group, the dataset includes data from animals subjected to splenectomy or to inhibition of LT biosynthesis with MK-886. The groups, as well as the analytes, are listed in a separate PDF file. Methodological details can be provided, upon request, by the principal investigator. |
| dc.description.sponsorship | FAPESP |
| dc.format | ZIP |
| dc.publisher | Alexandre Steiner |
| dc.subject | Inflammation |
| dc.title | Targeted lipidomics of prostaglandins and leukotrienes in a rat model of LPS-induced systemic inflammation |
| dc.type | Dataset |
| dc.description.sponsorshipId | 2018/03418-0 |
